March Madness: Sweet Sixteen Tips Off With Game Line Odds

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March Madness logo on ocurt

NCAAB circle logoThe 2025 March Madness tournament has reached the Sweet Sixteen round, and betting odds are still favorable to those looking to place bets.

Every year, the NCAAB season showdown starts with 64 teams playing for a chance to win the college basketball national championship.  Eventually, the competition dwindles to two teams playing for the right to call themselves NCAA Champions.

Future odds indicate who is favored to win the tournament, while game lines offer matchup odds. Below, we will discuss game lines and futures for the 2025 NCAAB postseason and the legal ways to bet on the competitions.

Sweet Sixteen Game Lines

One of the most popular ways to bet on college basketball is with game lines. Game line odds feature spread, totals, and money line odds, giving bettors three ways to bet on a matchup.

The Sweet Sixteen round will begin on Thursday, March 27th, and conclude the following day. Four games are scheduled for both Thursday and Friday. Elite 8 games will occur on Saturday, March 29th, and Sunday, March 30th, before the final four and national championship, which is scheduled for next week.

Below are the current game line odds for each of the sweet sixteen matchups from BetOnline’s sportsbook.

BYU (#6) vs. Alabama (#2)

  • Spread: +5.5 (-115), -5.5 (-105)
  • Win: +175, -210
  • Total: O175.0 (-110), U175.0 (-110)

Maryland (#4) vs. Florida (#1)

  • Spread: +6.5 (-105), -6.5 (-115)
  • Win: +235, -285
  • Total: O155.0 (-110), U155.0 (-110)

Arizona (#4) vs. Duke (#1)

  • Spread: +9.0 (-115), -9.0 (-105)
  • Win: +330, -440
  • Total: O154.0 (-110), U154.0 (-110)

Arkansas (#10) vs. Texas Tech (#3)

  • Spread: +5.5 (-110), -5.5 (-110)
  • Win: +195, -235
  • Total: O147.5 (-110), U147.5 (-110)

Mississippi (#6) vs. Michigan State (#2)

  • Spread: +3.0 (-110), -3.0 (-110)
  • Win: +135, -160
  • Total: O144.0 (-105), U144.0 (-115)

Kentucky (#3) vs. Tennessee (#2)

  • Spread: +4.0 (-115), -4.0 (-105)
  • Win: +145, -170
  • Total: O146.5 (-105), U146.5 (-115)

Michigan (#5) vs. Auburn (#1)

  • Spread: +8.0 (-110), -8.0 (-110)
  • Win: +290, -380
  • Total: O154.0 (-110), U154.0 (-110)

Purdue (#4) vs. Houston (#1)

  • Spread: +8.0 (-110), -8.0 (-110)
  • Win: +290, -380
  • Total: O133.0 (-110), U133.0 (-110)

March Madness Futures

Future odds are also very popular as they often offer great value to bettors who lock in their bets early. Even now, with only sixteen teams remaining, a $100 bet on Duke would pay out $215 if they come out on top.

Below are the current future odds from BetOnline. As you can see, Auburn has (+600) odds, which is incredible value given that the Tigers are one of the favorites to win the competition.

March Madness – National Champion Odds

  • Duke (#1) +215
  • Florida (#1) +375
  • Houston (#1) +500
  • Auburn (#1) +600
  • Alabama (#2) +1600
  • Tennessee (#2) +1600
  • Michigan State (#2) +2200
  • Texas Tech (#3) +2200
  • Maryland (#4) +2500
  • Arizona (#4) +4000
  • Kentucky (#3) +5500
  • Michigan (#5) +7000
  • Purdue (#4) +7000
  • Arkansas (#10) +7500
  • Mississippi (#6) +8500
  • BYU (#6) +9000

Is Online College Basketball Betting Legal In The Philippines?

No laws make gambling on sports online illegal in the Philippines. PH bettors can access offshore and domestic online sportsbooks regulated by the Philippine Amusement and Gaming Corporation (PAGCOR).

Basketball is one of the most popular sports in the Philippines, and online sportsbooks offer a wide range of odds. Some of the more popular leagues, including the NBA, PBA, and NCAA, are often featured in the futures and game line categories.

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